Retinoids and Contraception
نویسندگان
چکیده
منابع مشابه
Retinoids and cancer.
The synt hetic retinoids represent a new class of drugs wh ich a re highly effective in t he treatment of a broad spectrum of dermatologic d isease, including cystic acne, psori asis, and cutaneous di sorders of keratinization [1 3]. Moreover, t he use of synthetic retinoids in cancer prevent ion and therapy fo r both cutaneous and in te rna l t umors is potent ially the most signi ficant clini...
متن کاملRetinoids and Bone
Vitamin A (retinol) can be produced in the body by hydrolysis of retinyl esters or reduction of retinal. Liver and eggs, which are good animal sources of vitamin A, contain retinyl esters. Plant sources such as carrots and spinach contain pro-vitamin A carotenoids, which can be cleaved to retinal. Retinal, also called retinaldehyde, is interconvertible with retinol (Fig. 1). Retinal also serves...
متن کاملRetinoids and pulmonary hypertension.
BACKGROUND Retinoic acid has antimitogenic effects on smooth muscle cells. Studies on the systemic circulation suggest that it may reduce vascular thickening. Relationships between retinoids and pulmonary hypertension/pulmonary vascular remodeling, however, have not been explored. Thus, the present study examined retinoid levels in plasma of patients with idiopathic pulmonary arterial hypertens...
متن کاملRetinoids and Cardiac Development
Retinoic acid (RA), a derivative of vitamin A, is involved in signal transduction during vertebrate organogenesis. Retinoids through binding to nuclear receptors called RA receptors (RARs) and retinoid X receptors (RXRs) regulate various processes during cardiogenesis. Deregulated retinoid signaling thus has later consequences leading to cardiac malformations. In this review, we will summarize ...
متن کاملRetinoids and Retinal Diseases.
Recent progress in molecular understanding of the retinoid cycle in mammalian retina stems from painstaking biochemical reconstitution studies supported by natural or engineered animal models with known genetic lesions and studies of humans with specific genetic blinding diseases. Structural and membrane biology have been used to detect critical retinal enzymes and proteins and their substrates...
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ژورنال
عنوان ژورنال: Dermatology
سال: 1995
ISSN: 1018-8665,1421-9832
DOI: 10.1159/000246649